Is cinnamon good for depression?

RESULTS: This study showed that CE with dose of 25 mg/kg BW to dose 100 mg/k BW could reduce the duration of immobility when compared to the CMS group. Clinically, CE possessed the potential to reduce the duration of immobility and potentially reduce symptoms of depression.

oamjms.eu - Antidepressant Effect of Cinnamon (Cinnamomum burmannii) Bark ...

Which zodiac is broad minded?

Libra. Our list starts with Libra, an air sign whose symbol is the balanced scales. Libra values fairness, a trait that makes them notably open-...

Last updated Jul 25, 2021

Where is Adam & Eve buried?

The cave of Machpelah, in the West Bank city of Hebron, is the burial place of the Matriarchs and Patriarchs: Abraham, Isaac, Jacob, Sarah,...

Last updated Apr 7, 2018

Awaken your dormant DNA ability to attract wealth effortlessly

The simple yet scientifically proven Wealth DNA method laid out in the report allows you to effortlessly start attracting the wealth and abundance you deserve.

Learn More »

Promotion

Abstract

BACKGROUND: Depression is a psychiatric disorder that has become a serious health problem in the past decade. This disorder is characterized by prolonged dysphoric mood, and in more severe condition would result in decreased self-care and even life-threatening action. Serotonin is believed to play a role in the regulation of mood elation in depressive disorders. Decreased levels of serotonin in the hippocampus will cause an increased dopamine in mesolimbic dopamine neuronal cells. An effective and commonly used drug is the selective serotonin reuptake inhibitor, namely, fluoxetine. However, this agent has so many side effects, one of them is erectile dysfunction. In order to find the better treatment, exploration and discovery of therapeutic modalities need to pursued using natural materials. AIM: This study aimed to explore and evaluate antidepressant effects of cinnamon (Cinnamomum burmannii) extract (CE). METHODS: A total of 30 male Wistar rats were obtained from Eureka Research Laboratory (Palembang, Indonesia). Cinnamon simplisia was obtained from the Institute for Research and Testing of Traditional Medicine, Tawangmangu, Central Java, Indonesia. Rats were induced using chronic mild stress (CMS). CMS was a form of stress induction performed on experimental animals continuously, for 4 weeks. Forced swimming test (FST) was a test conducted to assess mobility in animal model. After induction for 4 weeks, rats were randomly divided into six groups which each contained five rats: Normal control group, CMS group (negative control), CMS + fluoxetin (Fluox 1: mg/kg), CMS + CE 25 mg/kg, the CMS + CE 50 mg/kg, and the CMS + CE 100 mg/kg. Treatment with fluoxetine or CE was given for 14 days intragastrically using gastric sonde. After treatment and FST, organ evacuation was performed and followed by immunohistochemistry and enzyme-linked immunosorbent examination. RESULTS: This study showed that CE with dose of 25 mg/kg BW to dose 100 mg/k BW could reduce the duration of immobility when compared to the CMS group. Clinically, CE possessed the potential to reduce the duration of immobility and potentially reduce symptoms of depression. Histologically, CE showed the potential to improve serotonin levels in the hippocampus with increasing doses. Tumor necrosis factor (TNF)-alpha expression in the hippocampus as a marker of inflammation had increased in the CMS group. CE was able to reduce the expression of TNF-alpha compared to the CMS group. CONCLUSION: CE possessed antidepressant efficacy by inhibiting the inflammatory process in the hippocampus so it was able to optimally increase serotonin levels in the hippocampus.

How much does TikTok pay if you go viral?

TikTok pays you for views using their Creator Fund(if you qualify). While the company doesn't fully disclose how much they pay creators, many have...

Last updated Nov 2, 2019

What are the 7 habits of millionaires?

If you want to get rich, here are seven “poverty habits” that handcuff people to a life of low income: Plan and set goals. Rich people are goal-...

Last updated May 24, 2019

Awaken your dormant DNA ability to attract wealth effortlessly

The simple yet scientifically proven Wealth DNA method laid out in the report allows you to effortlessly start attracting the wealth and abundance you deserve.

Learn More »

Promotion

How do I activate the wealth corner of my house?

When you stand at your bedroom door, the far left corner that you can see is the wealth corner. You can activate the wealth corner of your room by...

Last updated Mar 20, 2022

What business is booming in 2022?

Here are some of the business ideas that are likely to grow in 2022. ... Industries to consider for business ideas in 2022 Sustainability. ... Pet...

Last updated Jul 31, 2022

Awaken your dormant DNA ability to attract wealth effortlessly

The simple yet scientifically proven Wealth DNA method laid out in the report allows you to effortlessly start attracting the wealth and abundance you deserve.

Learn More »

Promotion

Do reels attract followers?

Reels are an effective way to reach an audience outside of your current followers. 50% of Instagram users find reels through the explore page. You...

Last updated Mar 19, 2021

Awaken your dormant DNA ability to attract wealth effortlessly

The simple yet scientifically proven Wealth DNA method laid out in the report allows you to effortlessly start attracting the wealth and abundance you deserve.

Learn More »

Promotion

What is the most superior gemstone?

1. Blue Diamond. The stunning blue diamond is arguably the most prized of all precious gemstones. A flawless example is so rare that whenever one...

Last updated Nov 27, 2019